As the Malaria Epidemic attacked people of these countries, carriers of the defective hemoglobin gene survived. Carrying one defective gene means that a person has a sickle cell trait. Two parents with the trait will produce a child with sickle thesis on sickle cell anemia anemia. People of these countries migrated and thesis on sickle cell anemia to other areas. In the Western ussmariner.com where malaria is not much of a problem, having the abnormal hemoglobin gene has lost its advantage.
Any child born from parents that each has the trait will be born with the disease.
Approximately, two million Americans carry the sickle cell trait. In Hispanic American births, one in every thousand people acquire sickle cell anemia. The theses on sickle cell anemia created by the blockage of blood flow can vary from patient to patient.
Some have milder symptoms than others. Physicians use Hand-foot syndrome on patients to determine the disease. Sickle cells that clog small blood vessels in the hands and feet are one characteristic of the disease.
Symptoms the patient suffers are thesis on sickle cell anemia of the hands, feet and various joints. The pain occurs in any joint or organ impulsively.
The amount of pain essay titled under pressure person. Patients may have painful episodes or ‘crises’, while for others; they may not be as painful. They can be as Jenkins 4 theses on sickle cell anemia as fifteen a year, or less than one time a year.
The pain can last for a few hours or several weeks. When the pain and swelling becomes too severe, patients are hospitalized and given intravenous fluids and painkillers.
The anemia causes pallor of the skin, fatigue, and shortness of breath. Hydroxyurea is a well-known drug, however its use in sickle thesis on sickle cell anemia disease is relatively new and must be approached with caution. Percent with severe pain times per year 5. Estimated number with frequent severe pain 3, Assuming the average annual number of episodes 4. The total number of severe thesis on sickle cell anemia episodes in these patients 13, Assuming the average days of hospitalization 5.
Estimated total number of hospital days for these patients 33, Estimates of sickle cell disease patients in the U. In the US there were approximately 65, disease.
There were about 5, British sufferers. Worldwide,babies are born with the disease annually. Sickle cell anemia results thesis on sickle cell anemia a person inherits two genes for sickle hemoglobin, and is homozygous for the mutation. American-Africans are the most likly to develope sickle cell anemia. Hemoglobin is composed of two pairs of peptide chains: Sickle hemoglobin results from a point mutation in the beta-globin gene.
This single nucleotide change produces a single amino acid homework exercises for 8 year olds Valine, on the other hand, is a neutral, or uncharged, amino acid. Under normal conditions it behaves like a hydrophobic, organic molecule and wants to hide from water.
This difference makes the globin chains of hemoglobin fold differently, especially in the absence of oxygen. Normal hemoglobin just gives up its oxygen when it gets to the tissue that needs it, but it retains its home-rent.mobin.uk and lack of oxygen, organs in patients with sickle cell disease commonly receive damage, which can cause these organs to malfunction.
Blindness can also occur in those with sickle research writing services disease due to decreased blood flow to the eyes. Skin ulcers are common in patients with the disease.
This is especially dangerous because ulcers are thesis on sickle cell anemia wounds that cause the body to become extremely susceptible to infection and disease.
Priapism can become prevalent in males with sickle cell anemia, due to the decreased amount of blood flow from the scrotum area that clots can cause. Treatment The standard of thesis on sickle cell anemia with sickle cell disease has increased is it illegal to write essays for money due to the latest medical advances.
Yet, sadly, the goal of sickle cell disease treatment is to treat the symptoms so that they become less prevalent, because no cure for the disease has been developed.